Tobey Maguire, Kirsten Dunst, James Franco, Alfred Molina, Rosemary Harris, J.K. Simmons

Sam Raimi

Peter Parker is struggling to manage both his personal life and his duties as Spider-Man, facing Dr. Otto Octavius, who after a failed experiment and his wife's death, uses his mechanical tentacles and threatens to endanger the lives of New York City's residents. Spider-Man must stop him from annihilating the city.